A lorry driver has been arrested over a fatal crash on the M6 in Staffordshire that left five people dead and a sixth person seriously injured.
Four women and a man all travelling in the car were killed in the collision between Stoke-on-Trent and Stafford in the early hours of Wednesday.
Another man who was also in the Nissan Micra suffered serious multiple injuries and is in a serious but stable condition.
The lorry driver, a 60-year-old man, was arrested on suspicion of causing death by dangerous driving and is being questioned by officers.
The motorway has been closed on the south-bound carriageway between junction 15 and junction 14, with police warning it will not reopen for some time.
A detailed police investigation is now under way to piece together the circumstances of the crash, which happened at around 4.30am.
One lane has reopened on the northbound carriageway between junction 11a and junction 12.
Delays stretched back to junction 16 and motorists are being urged to find an alternative route.
The ambulance service said the car's driver and four passengers had been killed after a "significant collision" involving an HGV.
One other occupant in the car, a man in his 40s, suffered multiple serious injuries and has been taken to Royal Stoke University Hospital.
In a statement, West Midlands Ambulance Service said: "When emergency services arrived they discovered a car with six occupants inside which had been involved in a significant collision with a HGV.
"Sadly, it quickly became apparent that nothing could be done to save the driver and four passengers.
"All five were confirmed dead on scene."
The male driver of the lorry was uninjured.
Police have appealed for any witnesses to get in touch by ringing 101.
Videos posted on social media showed miles of traffic which had built up behind the crash.